Reduced affinity of calcium sensing-receptor heterodimers and reduced mutant homodimer trafficking combine to impair function in a model of familial hypocalciuric hypercalcemia type 1.

Heterozygous loss-of-function mutation of the calcium sensing-receptor (CaSR), causes familial hypocalciuric hypercalcemia type 1 (FHH1), a typically benign condition characterized by mild hypercalcemia.In contrast, homozygous mutation of this dimer-forming G-protein coupled receptor manifests as the lethal neonatal severe hyperparathyroidism (NSHP

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Examination of Clinical, Endoscopy and One-Year Follow-Up Findings of Children with Accidental Ingestion of Caustic Substances Admitted to Shahid Sadoughi Hospital (2016-2019)

Introduction: Accidental ingestion of caustic substances can cause serious damage to the digestive system.This study was conducted with the aim of investigating the incidence of esophageal stricture within one year after accidental ingestion of caustic substances and its relationship with the first endoscopic findings in children.Methods: The prese

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A Comprehensive Review Uncovering the Challenges and Advancements in the In Vitro Propagation of Eucalyptus Plantations

The genus Eucalyptus is a globally captivated source of hardwood and is amina muaddi scarpe trasparenti well known for its medicinal uses.The hybrid and wild species of Eucalyptus are widely used as exotic plantations due to their renowned potential of adapting to various systems and sites, and rapid large-scale propagation of genetically similar p

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